NUDT1, nudix hydrolase 1, 4521

N. diseases: 73; N. variants: 3
Disease: Hyperplastic Polyp ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0333983
Disease: Hyperplastic Polyp
Hyperplastic Polyp 		0.010 GeneticVariation disease BEFREE To investigate the role of a defective 8-oxo-G repair we performed a germline mutation screening in the genes OGG1, MTH1 and MUTYH, in 81 patients with a clinical phenotype ranging from attenuated or atypical adenomatous polyposis coli including hyperplastic polyps to hereditary non-polyposis colorectal cancer (HNPCC) type X syndrome without mono- or biallelic mutations in either APC, MUTYH or the DNA mismatch repair genes. 21195604 2011