MTHFR, methylenetetrahydrofolate reductase, 4524

N. diseases: 816; N. variants: 57
Disease: Fetus affected by placental transfer of anticonvulsant ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1739111
Disease: Fetus affected by placental transfer of anticonvulsant
Fetus affected by placental transfer of anticonvulsant 		0.010 GeneticVariation disease BEFREE Mutation in the MTHFR gene in a mother taking sodium valproate, phenytoin or carbamazepine during pregnancy is associated with fetal anticonvulsant syndrome in her offspring. 10563481 1999