RNR2, l-rRNA, 4550

N. diseases: 76; N. variants: 4
Disease: Atherosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.040 Biomarker disease BEFREE Humanin (HN), a mitochondrial-derived peptide, was recently demonstrated to exert a protective role against endothelial dysfunction and Ox-LDL-induced progression of atherosclerosis. 31574567 2019
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.040 Biomarker disease BEFREE Humanin has been shown to protect cells from beta amyloid toxicity and preserve endothelial cell function in a mouse model of atherosclerosis. 30058454 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.040 Biomarker disease BEFREE Humanin (HN), a mitochondria-derived peptide, can prevent the production of reactive oxygen species and death of human aortic endothelial cells exposed to oxidized low-density lipoprotein (ox-LDL) and has a protective effect on patients with in early atherosclerosis. 27815075 2017
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.040 Biomarker disease BEFREE These findings suggest that HN may play a role and may have a protective effect in early atherosclerosis in humans. 20562421 2010