MUC2, mucin 2, oligomeric mucus/gel-forming, 4583

N. diseases: 225; N. variants: 12
Disease: Metaplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025568
Disease: Metaplasia
Metaplasia 		0.020 AlteredExpression phenotype LHGDN Upregulation of MUC2 reflects intestinal metaplasia in BE. 17401217 2007
CUI: C0025568
Disease: Metaplasia
Metaplasia 		0.020 AlteredExpression phenotype LHGDN In conclusion, this work demonstrates that Cdx-2 activates the expression of MUC2 mucin gene in gastric cells, inducing an intestinal transdifferentiation phenotype that parallels what is observed both in intestinal metaplasia and some gastric carcinomas. 14525978 2003