MVK, mevalonate kinase, 4598

N. diseases: 139; N. variants: 57
Disease: Infection by Trypanosoma evansi ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0276871
Disease: Infection by Trypanosoma evansi
Infection by Trypanosoma evansi 		0.010 GeneticVariation disease BEFREE <i>Trypanosoma evansi</i> is a flagellate protozoan parasite that causes the disease "Surra" in domesticated large mammals, with great economic impact.<i>T. evansi</i> has only a trypomastigote bloodstream form and requires constant modification of the variant surface glycoprotein (VSG) coat for protection against the host immune system.We identified MVK of <i>T. evansi</i> (termed TeMVK) and performed a preliminary characterization at molecular, biochemical, and cellular levels. 30042928 2018