MYB, MYB proto-oncogene, transcription factor, 4602

N. diseases: 206; N. variants: 30
Disease: Leukemia, T-Cell ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023492
Disease: Leukemia, T-Cell
Leukemia, T-Cell 		0.020 GeneticVariation disease BEFREE This study, together with previous and recent data showing rearrangements and copy number alterations of the MYB locus in T-cell leukemia and certain solid tumors, will be the main focus of this review. 20647765 2010
CUI: C0023492
Disease: Leukemia, T-Cell
Leukemia, T-Cell 		0.020 GeneticVariation disease BEFREE Strikingly, profiling of the T-ALLs by clinical, genomic, and large-scale gene expression analyses shows that the TCRB-MYB translocation defines a new T-ALL subtype associated with a very young age for T-cell leukemia (median, 2.2 years) and with a proliferation/mitosis expression signature. 17452517 2007