Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.030 Biomarker disease BEFREE Hence it is concluded that ICS II attenuates LPS-induced neuroinflammation through inhibiting TLR4/MyD88/NF-κB pathway in rats, and it has potential value as a new therapeutic agent to treat neuroinflammation-related diseases, such as AD. 30590319 2019
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.030 AlteredExpression disease BEFREE We have found that TLR2 and MyD88 levels are elevated in the hippocampus and cortex of patients with Alzheimer's disease (AD) and in a 5XFAD mouse model of AD. 29990310 2018
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.030 Biomarker disease BEFREE Our findings suggest that the MyD88-dependent pathway contributes to behavioral functions in an AD mouse model and its control group. 22051943 2012