SERPINC1, serpin family C member 1, 462

N. diseases: 184; N. variants: 46
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.050 Biomarker disease BEFREE Cutoff values for these factors were calculated using ROC analyses, and the combination of ATIII and U-P/Cr, which were poorly correlated, was predictive of AKI. 31269838 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.050 Biomarker disease BEFREE A higher requirement of PRBC transfusions was associated with pre-ECMO hematocrit, and with the following conditions during ECMO: platelet nadir, antithrombin III (ATIII), and stage 3 of acute kidney injury (all <i>P</i> < .05). 28460592 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.050 Biomarker disease BEFREE ATIII supplementation may have a potential prophylactic and therapeutic effect on SAP induced AKI. 28719489 2018
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.050 Biomarker disease BEFREE ATIII administration may represent a promising strategy for the prevention and treatment of contrast-induced AKI. 28219627 2017
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.050 GeneticVariation disease BEFREE To study this further, we generated SerpinC1 heterozygous knockout rats and followed the development of acute kidney injury in a model of modest renal ischemia/reperfusion injury. 26108065 2015