SERPINC1, serpin family C member 1, 462

N. diseases: 184; N. variants: 46
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036690
Disease: Septicemia
Septicemia
0.030 Biomarker disease BEFREE Consecutive ACLF patients without sepsis at baseline were assessed at days 0, 3 and 7 with thromboelastography (TEG) and specific assays (Factor VIII, von Willebrand factor [vWF], protein C and antithrombin III [ATIII]) and followed for development of sepsis, bleeding and outcome. 30589495 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.030 Biomarker disease BEFREE After 2DE, 20 significantly differently expressed spots were identified by mass spectrometry analysis, revealing deregulation of six different proteins upon sepsis and 50% were validated by ELISA: Antithrombin-III (AT-III), Clusterin (CLUS) and Serum amyloid A-1 (SAA-1). 28655573 2018
CUI: C0036690
Disease: Septicemia
Septicemia
0.030 Biomarker disease BEFREE The effects of therapeutically administering AT III after the onset of endotoxemia or sepsis were not clear. 27993201 2017