MYH2, myosin heavy chain 2, 4620

N. diseases: 77; N. variants: 25
Disease: Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 AlteredExpression group BEFREE Analysis of human melanoma biopsies revealed that amoeboid melanoma cells with high Myosin II activity are predominant in the invasive fronts of primary tumors in proximity to CD206<sup>+</sup>CD163<sup>+</sup> tumor-associated macrophages and vessels. 30712866 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 AlteredExpression group BEFREE We predict that altered 14-3-3 expression in humans inhibits the tumor suppressor myosin II, contributing to the changes in cell mechanics observed in many metastatic cancers. 29549125 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE Sds22/PP1 links epithelial integrity and tumor suppression via regulation of myosin II and JNK signaling. 21399659 2011
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE A specific isoform of nonmuscle myosin II-C is required for cytokinesis in a tumor cell line. 16790446 2006