MYP1, myopia 1 (X-linked), 4657

N. diseases: 7; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.080 Biomarker disease BEFREE The unique LVAVA haplotype in OPN1LW was detected in the family with X-linked nonsyndromic high myopia mapped to MYP1. 26114493 2015
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.080 GeneticVariation disease BEFREE Refinement of the X-linked nonsyndromic high-grade myopia locus MYP1 on Xq28 and exclusion of 13 known positional candidate genes by direct sequencing. 21357393 2011
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.080 GeneticVariation disease BEFREE In addition, our results suggest that color visual defects and optic disc hypoplasia are not necessary signs of high myopia attributed to the MYP1 region. 21060050 2010
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.080 GeneticVariation disease BEFREE Many genetic mutations linked to the development of HM have been described, including high grade myopia, and MYP1-16; different patterns of inheritance may reflect different types of HM. 19865068 2009
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.080 GeneticVariation disease BEFREE Evaluation of the X-linked high-grade myopia locus (MYP1) with cone dysfunction and color vision deficiencies. 19098318 2009
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.080 Biomarker disease BEFREE Confirmation of a genetic locus for X-linked recessive high myopia outside MYP1. 17351708 2007
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.080 Biomarker disease BEFREE Novel locus for X linked recessive high myopia maps to Xq23-q25 but outside MYP1. 16648373 2006
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.080 GeneticVariation disease BEFREE The disease maps to chromosome Xq28 and is the first designated high-grade myopia locus (MYP1). 15197065 2004
CUI: C0027092
Disease: Myopia
Myopia 		0.020 Biomarker disease BEFREE Two large multigeneration Asian Indian pedigrees (UR006 and UR077) with isolated, nonsyndromic myopia were studied, in which the condition appeared to segregate as an X-linked recessive trait (MYP1; MIM 310460). 21357393 2011
CUI: C0027092
Disease: Myopia
Myopia 		0.020 GeneticVariation disease BEFREE This new myopia locus is outside the linked region of the first high myopia locus (MYP1). 16648373 2006
CUI: C1298695
Disease: Hypoplasia of optic disc
Hypoplasia of optic disc 		0.010 Biomarker disease BEFREE In addition, our results suggest that color visual defects and optic disc hypoplasia are not necessary signs of high myopia attributed to the MYP1 region. 21060050 2010
CUI: C0009398
Disease: Color vision defect
Color vision defect 		0.010 GeneticVariation phenotype BEFREE Evaluation of the X-linked high-grade myopia locus (MYP1) with cone dysfunction and color vision deficiencies. 19098318 2009
CUI: C0242225
Disease: Color blindness
Color blindness 		0.010 GeneticVariation disease BEFREE Evaluation of the X-linked high-grade myopia locus (MYP1) with cone dysfunction and color vision deficiencies. 19098318 2009
CUI: C0543968
Disease: Cone dysfunction syndrome
Cone dysfunction syndrome 		0.010 GeneticVariation disease BEFREE Evaluation of the X-linked high-grade myopia locus (MYP1) with cone dysfunction and color vision deficiencies. 19098318 2009
CUI: C1839612
Disease: MYOPIA 1, X-LINKED
MYOPIA 1, X-LINKED 		0.010 Biomarker disease BEFREE TEX28 gene CNVs appear to be associated with the MYP1 X-linked myopia phenotypes. 19098318 2009