ATF4, activating transcription factor 4, 468

N. diseases: 178; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0043124
Disease: West Nile Fever
West Nile Fever
0.010 Biomarker disease BEFREE While LGP2 functions to modulate inflammatory signaling, RIG-I and MDA5 together are essential for M1 macrophage polarization in vivo and the control of WNV infection through potential downstream control of ATF4 and SMAD4 to regulate target gene expression for cell polarization. 31409781 2019