ATF4, activating transcription factor 4, 468

N. diseases: 178; N. variants: 4
Disease: HIV-1 infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.020 AlteredExpression disease BEFREE This report identifies for the first time ATF4 as a transcription factor upregulated by HIV-1 infection. 22050711 2012
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.020 AlteredExpression disease BEFREE These genes encode a host of proteins with divergent functions in a variety of cellular processes including apoptosis (FAS, Fas ligand, PIN, HSP90beta, bcl-2, bcl-x), cell signal transduction (Ras, RGS1, IRF-1, STAT3), receptor-mediated signaling transduction (CD71, CD69, CD3delta), cell cycle and growth (c-myc, cytokines, kinase), transcriptional regulation (EWS, CREB-2), and chemotaxis (beta-chemokines, RANTES), supporting the general effects of HIV-1 infection on cells of different origin. 15885842 2005