ATM, ATM serine/threonine kinase, 472

N. diseases: 684; N. variants: 974
Disease: Pancreatic Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.330 AlteredExpression disease BEFREE Furthermore, ATM silencing increased PD-L1 expression and increased the sensitivity of pancreatic tumors to PD-L1-blocking antibody in association with increased tumoral CD8<sup>+</sup> T cells and established immune memory. 31101760 2019
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.330 Biomarker disease BEFREE More importantly, ATM deficiency also renders murine pancreatic tumors highly sensitive to radiation. 28894253 2017
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.330 Biomarker disease CTD_human Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer. 26098869 2015
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.330 Biomarker disease CTD_human Loss-of-function variants in ATM confer risk of gastric cancer. 26098866 2015
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.330 Biomarker disease BEFREE Moreover, Fanconi anemia complementation group G- (FANCG-) and FANCC-deficient pancreatic tumor lines were more sensitive to the ATM inhibitor KU-55933 than isogenic corrected lines. 17431503 2007