NEDD8, NEDD8 ubiquitin like modifier, 4738

N. diseases: 88; N. variants: 2
Disease: Acute myeloid leukaemia refractory ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		0.010 AlteredExpression disease BEFREE Pevonedistat (TAK-924/MLN4924) is a novel inhibitor of NEDD8-activating enzyme (NAE) with single-agent activity in relapsed/refractory acute myeloid leukemia (AML). 29348128 2018