NFE2L2, nuclear factor, erythroid 2 like 2, 4780

N. diseases: 823; N. variants: 34
Disease: Liver Abscess, Amebic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023886
Disease: Liver Abscess, Amebic
Liver Abscess, Amebic 		0.020 Biomarker disease BEFREE This suggests that the adrenergic system may be involved in oxidative stress and in modulation of the Nrf2 and NF-κB pathways during ALA development. 29185982 2017
CUI: C0023886
Disease: Liver Abscess, Amebic
Liver Abscess, Amebic 		0.020 Biomarker disease BEFREE Otherwise, Nrf2 and superoxide dismutase-1, decreased at 48 h and catalase declined at 36 and 48 h. Furthermore, heme oxygenase-1 was increased at 12 and 24 h and decreased to normal levels at 36 and 48 h. These findings suggest for the first time that the host antioxidant system of Nrf2 is influenced during ALA. 27876112 2017