NFE2L2, nuclear factor, erythroid 2 like 2, 4780

N. diseases: 823; N. variants: 34
Disease: Skin Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0037286
Disease: Skin Neoplasms
Skin Neoplasms 		0.310 Biomarker group BEFREE Here we show that the incidence, multiplicity, and burden of solar-simulated UV radiation-mediated cutaneous tumors that form in SKH-1 hairless mice in which Nrf2 is genetically constitutively activated are lower than those that arise in their wild-type counterparts. 25804610 2015
CUI: C0037286
Disease: Skin Neoplasms
Skin Neoplasms 		0.310 Biomarker group CTD_human Arsenic-induced malignant transformation of human keratinocytes: involvement of Nrf2. 18572023 2008