NFE2L2, nuclear factor, erythroid 2 like 2, 4780

N. diseases: 823; N. variants: 34
Disease: Endometrial Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.360 Biomarker disease BEFREE We aimed to identify molecular alterations associated with NRF2 activation in endometrial carcinoma (EC). 30908539 2019
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.360 AlteredExpression disease BEFREE Nrf2, Keap1 and DJ-1 expression in endometrial carcinomas was analyzed immunohistochemically. 30711933 2019
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.360 Biomarker disease BEFREE Transfection of Nrf2 and survivin into endometrial cancer cells in vitro was done to determine the roles of Nrf2 and survivin in progestin resistance. 28386373 2017
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.360 Biomarker disease BEFREE We identified networks regulated by known cancer drivers such as GATA3 and FOXA1 (breast cancer), SOX17 and FOXA2 (endometrial cancer), and NFE2L2, SOX2, and TP63 (squamous cell lung cancer). 25994056 2015
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.360 Biomarker disease BEFREE To understand the role of Keap1 and Nrf2 in endometrial cancer, we performed DNA sequencing of tumors and noted the relation of the DNA sequence with annotated clinicopathologic data. 21897267 2011
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.360 Biomarker disease CTD_human High levels of Nrf2 determine chemoresistance in type II endometrial cancer. 20530669 2010
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.360 AlteredExpression disease BEFREE High levels of Nrf2 determine chemoresistance in type II endometrial cancer. 20530669 2010