NFE2L2, nuclear factor, erythroid 2 like 2, 4780

N. diseases: 823; N. variants: 34
Disease: Drug-Induced Acute Liver Injury ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury 		0.300 Therapeutic disease CTD_human Nrf2 Activation Ameliorates Hepatotoxicity Induced by a Heme Synthesis Inhibitor. 30215777 2019
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury 		0.300 Therapeutic disease CTD_human P450 3A-Catalyzed O-Dealkylation of Lapatinib Induces Mitochondrial Stress and Activates Nrf2. 26958860 2016
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury 		0.300 Therapeutic disease CTD_human Nrf2 protects against furosemide-induced hepatotoxicity. 24813929 2014
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury 		0.300 Therapeutic disease CTD_human Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation. 22627062 2012
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury 		0.300 Therapeutic disease CTD_human Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury. 22491424 2012