NFKB1, nuclear factor kappa B subunit 1, 4790

N. diseases: 551; N. variants: 52
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.040 GeneticVariation disease BEFREE Genetic polymorphisms in PXR and NF-κB1 influence susceptibility to anti-tuberculosis drug-induced liver injury. 31490979 2019
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.040 Biomarker disease BEFREE Moreover, genetic studies in patients suggest that SP110 plays a key role in modulating TB susceptibility in concert with NFκB1 and TNFα genes. 27858493 2017
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.040 Biomarker disease BEFREE KLF5, CEBPA and NFKB1 for TB; FOXP2, BRCA1, CEBPB, CREB1, EBF1 and ZNF354C for HIV/AIDS; and RUNX2, HIF1A, JUN/AP-1, NR4A2, EGR1 for both diseases). 26447748 2015
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.040 GeneticVariation disease BEFREE This SNP, located at 14bp upstream of a NF-kB binding site, might also account for the susceptibility to TB. 19523460 2009