|
Depressive disorder
|
0.360 |
Biomarker
|
disease |
BEFREE |
In this study, we examined the association between single-nucleotide polymorphisms of the genes encoding SOD2 (superoxide dismutase 2), CAT (catalase), GPx4 (glutathione peroxidase 4), NOS1 (nitric oxide synthase 1), NOS2 (nitric oxide synthase 2), and the development of depressive disorders.
|
29331597 |
2018 |
|
Depressive disorder
|
0.360 |
AlteredExpression
|
disease |
BEFREE |
We previously demonstrated that cyclic AMP-dependent protein kinase (PKA) phosphorylates neuronal nitric oxide synthase (nNOS) at Ser<sup>1412</sup> in the hippocampal dentate gyrus after forebrain ischemia; this phosphorylation event activates NOS activity and might contribute to depression after cerebral ischemia.
|
29074292 |
2018 |
|
Depressive disorder
|
0.360 |
Biomarker
|
disease |
BEFREE |
The Utility of Low-Dose Aripiprazole for the Treatment of Bipolar II and Bipolar NOS Depression.
|
27977470 |
2017 |
|
Depressive disorder
|
0.360 |
Biomarker
|
disease |
BEFREE |
We aimed to determine the NO content in the cerebrospinal fluid (CSF) and the expression of NO synthase (NOS) isoforms, that is, NOS1, NOS2, and NOS3 in the ACC in depression.
|
22989585 |
2013 |
|
Depressive disorder
|
0.360 |
Biomarker
|
disease |
PSYGENET |
We aimed to determine the NO content in the cerebrospinal fluid (CSF) and the expression of NO synthase (NOS) isoforms, that is, NOS1, NOS2, and NOS3 in the ACC in depression.
|
22989585 |
2013 |
|
Depressive disorder
|
0.360 |
Biomarker
|
disease |
BEFREE |
Having a first-degree relative with symptoms of bipolar disorder and having a loaded pedigree for diagnosis of depression each were associated with conversion from BD-NOS to BD-I or II (odds ratio range: 1.09-3.14; relative risk range: 1.06-2.34).
|
22959237 |
2013 |
|
Depressive disorder
|
0.360 |
Biomarker
|
disease |
PSYGENET |
This study replicates the previous finding of a high rate of conversion from BD-NOS to BD-I or II among youth, and suggests conversion is related to symptoms of bipolar disorder or depression diagnoses in the family history.
|
22959237 |
2013 |
|
Depressive disorder
|
0.360 |
Biomarker
|
disease |
PSYGENET |
These results suggest that urea accumulation in the hippocampus induced by UT-B deletion can cause depression-like behavior, which possibly attribute to disturbance in NOS/NO system.
|
21750947 |
2012 |
|
Depressive disorder
|
0.360 |
Biomarker
|
disease |
BEFREE |
Six genes were identified as of interest for a follow-up, based on the strength of the association and based on the interest as potential candidate target for developing new treatment for depression: Solute Carrier Family 4 Member 10 (SLC4A10), Dipeptidyl Peptidase IV (DPP4), Dopamine Receptor D3 (DRD3), Zinc Finger Protein 80 (ZNF80), Nitric Oxide Synthase 2A (NOS2A) and Peroxisome Proliferator-Activated Receptor-Gamma, Coactivator 1, Alpha (PPARGC1A).
|
21630437 |
2011 |
|
Depressive disorder
|
0.360 |
Biomarker
|
disease |
PSYGENET |
Six genes were identified as of interest for a follow-up, based on the strength of the association and based on the interest as potential candidate target for developing new treatment for depression: Solute Carrier Family 4 Member 10 (SLC4A10), Dipeptidyl Peptidase IV (DPP4), Dopamine Receptor D3 (DRD3), Zinc Finger Protein 80 (ZNF80), Nitric Oxide Synthase 2A (NOS2A) and Peroxisome Proliferator-Activated Receptor-Gamma, Coactivator 1, Alpha (PPARGC1A).
|
21630437 |
2011 |
|
Depressive disorder
|
0.360 |
Biomarker
|
disease |
PSYGENET |
Endogenous nitric oxide is a key promoting factor for initiation of seizure-like events in hippocampal and entorhinal cortex slices.
|
19571147 |
2009 |