NOS2, nitric oxide synthase 2, 4843

N. diseases: 783; N. variants: 28
Disease: Seizures ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036572
Disease: Seizures
Seizures 		0.320 Biomarker phenotype BEFREE Then followed by co-injection of its sub-effective dose and NOS inhibitors including 7-Nitroindazole (7-NI), aminoguanidine (AG) and L-N<sup>G</sup>-Nitroarginine methyl ester (L-NAME) to evaluate the changes in seizure threshold and the possible involvement of nitrergic system. 31202800 2019
CUI: C0036572
Disease: Seizures
Seizures 		0.320 Biomarker phenotype CTD_human Pharmacological inhibition of inducible nitric oxide synthase attenuates the development of seizures in mice. 19559095 2009
CUI: C0036572
Disease: Seizures
Seizures 		0.320 Biomarker phenotype BEFREE Treatment of virus-infected animals with the NOS inhibitor Nomega-monomethyl-l-arginine (l-NMMA), but not Nomega-monomethyl-d-arginine, significantly ameliorated not only clinical symptoms such as paralysis and seizures but also mortality. 10191185 1999