NOS3, nitric oxide synthase 3, 4846

N. diseases: 706; N. variants: 39
Disease: Diabetic Nephropathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 GeneticVariation disease BEFREE Studies exploring gene and environment interactions with endothelial nitric oxide synthase polymorphisms may help understand better the genetics of diabetic nephropathy. 19773668 2009
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 GeneticVariation disease LHGDN We evaluated the association of the constitutive endothelial nitric oxide synthase gene (eNOS) polymorphisms with type 2 diabetic nephropathy. 18401556 2008
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 GeneticVariation disease BEFREE We evaluated the association of the constitutive endothelial nitric oxide synthase gene (eNOS) polymorphisms with type 2 diabetic nephropathy. 18401556 2008
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 GeneticVariation disease BEFREE We evaluated the association of -786T>C (promoter region), Glu298Asp (Exon 7), and 4b4a (Intron 4) polymorphisms in eNOS gene with Type 2 diabetes mellitus (T2DM) and DN by haplotype analysis. 18413207 2008
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 GeneticVariation disease BEFREE Logistic regression analysis identified SNPs AGER 2184A/G and NOS3 774C/T, together with diabetes duration and HbA1c, as significant predictors of DN. 17345061 2007
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 GeneticVariation disease BEFREE We therefore studied association between DN and two polymorphisms in NOS3, Glu298Asp and NOS4ab, in Caucasian type 1 diabetes (T1D) patients. 17101543 2006
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 GeneticVariation disease BEFREE This study aimed to elucidate the roles of eNOS and the angiotensin-converting enzyme (ACE) gene polymorphism for the progression of type 2 diabetic nephropathy (DN). 15331206 2004
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 GeneticVariation disease BEFREE We conclude that there is no association of the ecNOS gene polymorphism with the development of diabetic nephropathy in Japanese patients with type 2 diabetes. 12413777 2002
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 GeneticVariation disease LHGDN We conclude that there is no association of the ecNOS gene polymorphism with the development of diabetic nephropathy in Japanese patients with type 2 diabetes. 12413777 2002
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 GeneticVariation disease BEFREE These results imply that the ecNOS gene polymorphism may be associated with progression to diabetic nephropathy in Japanese type 2 diabetic patients. 10868974 2000
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 GeneticVariation disease BEFREE Lack of association between an ecNOS gene polymorphism and diabetic nephropathy in type 2 diabetic patients with proliferative diabetic retinopathy. 10741691 2000