NOS3, nitric oxide synthase 3, 4846

N. diseases: 706; N. variants: 39
Disease: Persistent Fetal Circulation Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0031190
Disease: Persistent Fetal Circulation Syndrome
Persistent Fetal Circulation Syndrome 		0.210 PosttranslationalModification disease BEFREE PPHN significantly increased the DNA CpG methylation in eNOS promoter and decreased TET activity in PAEC. 30004838 2018
CUI: C0031190
Disease: Persistent Fetal Circulation Syndrome
Persistent Fetal Circulation Syndrome 		0.210 Biomarker disease MGD Endothelial injury due to eNOS deficiency accelerates the progression of chronic renal disease in the mouse. 19036847 2009
CUI: C0031190
Disease: Persistent Fetal Circulation Syndrome
Persistent Fetal Circulation Syndrome 		0.210 Biomarker disease MGD Intrauterine growth retardation in endothelial nitric oxide synthase-deficient mice is established from early stages of pregnancy. 18256327 2008
CUI: C0031190
Disease: Persistent Fetal Circulation Syndrome
Persistent Fetal Circulation Syndrome 		0.210 Biomarker disease MGD Disruption of the endothelial nitric oxide synthase gene affects ovulation, fertilization and early embryo survival in a knockout mouse model. 18663015 2008
CUI: C0031190
Disease: Persistent Fetal Circulation Syndrome
Persistent Fetal Circulation Syndrome 		0.210 Biomarker disease MGD Lack of endothelial nitric-oxide synthase leads to progressive focal renal injury. 17200185 2007
CUI: C0031190
Disease: Persistent Fetal Circulation Syndrome
Persistent Fetal Circulation Syndrome 		0.210 Biomarker disease MGD Bone re/modeling is more dynamic in the endothelial nitric oxide synthase(-/-) mouse. 16763060 2006
CUI: C0031190
Disease: Persistent Fetal Circulation Syndrome
Persistent Fetal Circulation Syndrome 		0.210 Biomarker disease MGD Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. 15841206 2005
CUI: C0031190
Disease: Persistent Fetal Circulation Syndrome
Persistent Fetal Circulation Syndrome 		0.210 Biomarker disease MGD Defective lung vascular development and fatal respiratory distress in endothelial NO synthase-deficient mice: a model of alveolar capillary dysplasia? 15016731 2004
CUI: C0031190
Disease: Persistent Fetal Circulation Syndrome
Persistent Fetal Circulation Syndrome 		0.210 Biomarker disease MGD Genetic Models in Applied Physiology. Differential role of nitric oxide synthase isoforms in fever of different etiologies: studies using Nos gene-deficient mice. 12562678 2003
CUI: C0031190
Disease: Persistent Fetal Circulation Syndrome
Persistent Fetal Circulation Syndrome 		0.210 Biomarker disease MGD Development of heart failure and congenital septal defects in mice lacking endothelial nitric oxide synthase. 12176963 2002
CUI: C0031190
Disease: Persistent Fetal Circulation Syndrome
Persistent Fetal Circulation Syndrome 		0.210 Biomarker disease MGD Abnormal aortic valve development in mice lacking endothelial nitric oxide synthase. 10821808 2000