NOTCH1, notch receptor 1, 4851

N. diseases: 693; N. variants: 64
Disease: Malignant neoplasm of skin ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.330 Biomarker disease BEFREE Targeting Notch1 and IKKα Enhanced NF-κB Activation in CD133<sup>+</sup> Skin Cancer Stem Cells. 29959199 2018
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.330 Biomarker disease CTD_human Whole-Exome Sequencing Validates a Preclinical Mouse Model for the Prevention and Treatment of Cutaneous Squamous Cell Carcinoma. 27923803 2017
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.330 Biomarker disease BEFREE Our results suggest NOTCH1 is a potential target for discovery of new drug to inhibit skin cancer metastasis. 22038626 2012
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.330 AlteredExpression disease BEFREE Present findings show divergent expression of Notch 1 in skin cancer, depending on anatomical site and tumor histotype. 18192969 2008