Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.550 Biomarker disease BEFREE Systemic Central Nervous System (CNS)-targeted Delivery of Neuropeptide Y (NPY) Reduces Neurodegeneration and Increases Neural Precursor Cell Proliferation in a Mouse Model of Alzheimer Disease. 26620558 2016
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.550 AlteredExpression disease BEFREE The effect of neuropeptide Y on cell survival and neurotrophin expression in in-vitro models of Alzheimer's disease. 25026432 2015
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.550 Therapeutic disease RGD We suggest that NPY, perhaps acting via NPY Y1 receptors, might interact with the endogenous cholinergic system and play a role in improving the learning and memory processes in the rats with AD-like condition. 22266216 2012
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.550 Therapeutic disease RGD Nicotine evoked improvement in learning and memory is mediated through NPY Y1 receptors in rat model of Alzheimer's disease. 22266216 2012
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.550 Therapeutic disease RGD We investigated the role of endogenous neuropeptide Y (NPY) system in nicotine-mediated improvement of learning and memory in rat model of Alzheimer's disease (AD). 22266216 2012
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.550 Biomarker disease BEFREE Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease. 19176820 2009
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.550 GeneticVariation disease BEFREE Polymorphism in neuropeptide Y influences CSF cholesterol levels but is no major risk factor of Alzheimer's disease. 15959845 2006
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.550 Biomarker disease CTD_human During the last two decades, NPY body fluid concentrations and NPY/PYY brain receptor numbers have been demonstrated to be altered during the course of Alzheimer's disease. 11709213 2002
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.550 Biomarker disease CTD_human Neuropeptide Y, peptide YY and aluminum in Alzheimer's disease: is there an etiological relationship? 11709213 2002
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.550 Biomarker disease BEFREE The leucine (7)-to-proline (7) polymorphism in the signal peptide of neuropeptide Y is not associated with Alzheimer's disease or the link apolipoprotein E. 10841982 2000