NPR2, natriuretic peptide receptor 2, 4882

N. diseases: 122; N. variants: 30
Disease: Anovulatory (finding) ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0429468
Disease: Anovulatory (finding)
Anovulatory (finding) 		0.020 AlteredExpression disease BEFREE Dehydroepiandrosterone (DHEA) treatment caused anovulation, high levels of androgen and estrogen receptors (AR and ER) in the ovary, high expression of CNP and natriuretic peptide receptor 2 (NPR2) in granulosa cells (GC), and an increase in testosterone and estradiol (E<sub>2</sub>) levels in sera. 29739821 2018
CUI: C0429468
Disease: Anovulatory (finding)
Anovulatory (finding) 		0.020 AlteredExpression disease BEFREE Here, based on a dehydroepiandrosterone (DHEA)-induced PCOS-like mouse model, persistent high levels of CNP/NPR2 were detected in anovulation ovaries. 29535265 2018