NRGN, neurogranin, 4900

N. diseases: 69; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.030 Biomarker group BEFREE Moreover, linagliptin treatment after stroke decreased the presence of peptides derived from neurogranin and from an isoform of the myelin basic protein. 29776406 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.030 Biomarker group BEFREE These data collectively indicated that HNG has neuroprotective effects against OGD/R by reactivating Jak2/Stat3 signaling through the PI3K/AKT pathway, suggesting that HNG may be a promising agent in the management of stroke. 29043002 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.030 AlteredExpression group BEFREE In contrast to tau, of which high levels in both CSF and plasma were related to stroke characteristics like severity and long-term outcome, plasma neurogranin levels were only correlated with infarct volume. 28854881 2017