NRGN, neurogranin, 4900

N. diseases: 69; N. variants: 4
Disease: Cerebral atrophy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0235946
Disease: Cerebral atrophy
Cerebral atrophy 		0.020 Biomarker disease BEFREE In contrast, Ng was associated with regional brain atrophy only in individuals with Aβ pathology. 28692877 2017
CUI: C0235946
Disease: Cerebral atrophy
Cerebral atrophy 		0.020 AlteredExpression disease BEFREE The CSF neurogranin levels correlated with brain atrophy (normalized whole-brain volumes: adjusted r = -0.38, P = .02; hippocampal volumes: adjusted r = -0.36, P = .03; entorhinal volumes: adjusted r = -0.46, P = .006; and parahippocampal volumes: adjusted r = -0.47, P = .005, n = 38) in AD and with amyloid load (r = 0.39, P = .02, n = 36) in preclinical AD. 27018940 2016