NRGN, neurogranin, 4900

N. diseases: 69; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4041080
Disease: Neurocognitive Disorders
Neurocognitive Disorders
0.020 Biomarker group BEFREE This either indicates that synaptic injury is not an important part of HIV neuropathogenesis or that CSF neurogranin is not sensitive to the type of synaptic impairment present in HIV-associated neurocognitive disorders. 30649659 2019
CUI: C4041080
Disease: Neurocognitive Disorders
Neurocognitive Disorders
0.020 Biomarker group BEFREE Synaptic damage in HAND+ patients could be a result of abrogation of Ng through HIV-1-induced inflammation that dysregulates Ng-CaM interaction and downstream signaling cascades associated with synaptodendritic functions. 29703241 2018