Disease: Huntington Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020179
Disease: Huntington Disease
Huntington Disease 		0.050 Biomarker disease BEFREE High and Low Levels of an NTRK2-Driven Genetic Profile Affect Motor- and Cognition-Associated Frontal Gray Matter in Prodromal Huntington's Disease. 29932126 2018
CUI: C0020179
Disease: Huntington Disease
Huntington Disease 		0.050 Biomarker disease BEFREE Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease. 23446639 2013
CUI: C0020179
Disease: Huntington Disease
Huntington Disease 		0.050 AlteredExpression disease BEFREE Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies. 23598407 2013
CUI: C0020179
Disease: Huntington Disease
Huntington Disease 		0.050 Biomarker disease BEFREE As this phenotype develops in the presence of normal levels of brain-derived neurotrophic factor and its major striatal receptor, tropomyosin-related kinase B, these data represent the first demonstration of in vivo cell-autonomous transcriptional dysregulation in an HD mouse model. 18632688 2008
CUI: C0020179
Disease: Huntington Disease
Huntington Disease 		0.050 Biomarker disease BEFREE We found a specific reduction of TrkB receptors in transgenic exon-1 and full-length knock-in HD mouse models and also in the motor cortex and caudate nucleus of HD brains. 16487146 2006