NTS, neurotensin, 4922

N. diseases: 184; N. variants: 1
Disease: Constipation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009806
Disease: Constipation
Constipation 		0.020 GeneticVariation phenotype BEFREE Interestingly, at the dose providing 90% pain relief, the co-administration of morphine with An2-NT(8-13) had a reduced effect on constipation. 30707956 2019
CUI: C0009806
Disease: Constipation
Constipation 		0.020 GeneticVariation phenotype BEFREE To investigate whether pathophysiological differences exist among healthy controls (HC) and patients with slow and normal transit constipation (STC and NTC), we evaluated (1) gastrointestinal (GI) symptoms using validated questionnaires; (2) circulating concentrations of neurotensin, motilin, corticotrophin-releasing factor (CRF), and somatostatin; and (3) possible differences in frequency distribution of the neurotensin rs1800832 A/G and Neurotensin Receptor 1 rs6090453 C/G SNPs. 29082242 2017