NTS, neurotensin, 4922

N. diseases: 184; N. variants: 1
Disease: Agnosia for Pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		0.050 Biomarker disease BEFREE Besides, NT analogs exert strong opioid-independent analgesia. 30707956 2019
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		0.050 GeneticVariation disease BEFREE Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia. 31589400 2019
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		0.050 Biomarker disease BEFREE The peptide neurotensin (Nts) was discovered within the brain over 40years ago and is implicated in regulating analgesia, body temperature, blood pressure, locomotor activity and feeding. 29288794 2018
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		0.050 Biomarker disease BEFREE Neurotensin exerts potent analgesia by acting at both NTS1 and NTS2 receptors, whereas NTS1 activation also results in other physiological effects such as hypotension and hypothermia. 28368584 2017
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		0.050 Biomarker disease BEFREE Neurotensin (NT) can produce a profound analgesia or enhance pain responses, depending on the circumstances. 16870306 2006