Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease PSYGENET These data show a deficient prefrontal NGFI-B and Nurr1 expression in schizophrenia and bipolar disorder. 16631355 2006
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 AlteredExpression disease BEFREE These data show a deficient prefrontal NGFI-B and Nurr1 expression in schizophrenia and bipolar disorder. 16631355 2006
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 GeneticVariation disease BEFREE To test the hypothesis that genetic variants of the retinoid receptor genes may predispose to schizophrenia and other psychiatric diseases, the six RAR and RXR genes and a heterodimer partner, the NURR1 gene, were scanned in 100 schizophrenia patients, along with pilot studies in 20-24 patients with bipolar disorder (BPD), attention-deficit hyperactivity disorder (ADHD), autism, or alcoholism. 15635645 2005
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 GeneticVariation disease BEFREE Evidence by others support this hypothesis (1) mapping of the NR4A2 gene to chromosome 2q22-23, a region with suggestive linkage to schizophrenia and (2) identification of mutations in patients with schizophrenia (c.366-369delTAC, c.308A > G, c.-469delG), manic depression (c.289A > G), and familial Parkinson's disease (c.-291delT, c.-245T > G). 15211629 2004
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 GeneticVariation disease BEFREE NURR1 mutations in cases of schizophrenia and manic-depressive disorder. 11121187 2000