OGG1, 8-oxoguanine DNA glycosylase, 4968

N. diseases: 313; N. variants: 38
Disease: Angiomyolipoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206633
Disease: Angiomyolipoma
Angiomyolipoma 		0.030 AlteredExpression disease BEFREE We recently show that the constitutive expression of OGG1 in heterozygous (TSC2+/-) Eker rat and in angiomyolipomas kidney tissue from human is 2-3fold less than in kidney from wild-type rats and control human subjects. 20687497 2010
CUI: C0206633
Disease: Angiomyolipoma
Angiomyolipoma 		0.030 Biomarker disease BEFREE These data suggest that tuberin and OGG1 are important proteins in the pathogenesis of angiomyolipoma in TSC patients. 19265534 2009
CUI: C0206633
Disease: Angiomyolipoma
Angiomyolipoma 		0.030 GeneticVariation disease LHGDN Association analysis showed the presence of significant association (p = 0.01) only between the Ser(326)Cys polymorphism of OGG1 and angiomyolipoma. 17932460 2008
CUI: C0206633
Disease: Angiomyolipoma
Angiomyolipoma 		0.030 GeneticVariation disease BEFREE Association analysis showed the presence of significant association (p = 0.01) only between the Ser(326)Cys polymorphism of OGG1 and angiomyolipoma. 17932460 2008