OPRK1, opioid receptor kappa 1, 4986

N. diseases: 156; N. variants: 12
Disease: child abuse behavior ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008060
Disease: child abuse behavior
child abuse behavior 		0.010 AlteredExpression phenotype BEFREE A history of child abuse specifically associated in the anterior insula with a downregulation of the kappa opioid receptor (Kappa), as well as decreased DNA methylation in the second intron of the Kappa gene. 28886759 2018