OPRK1, opioid receptor kappa 1, 4986

N. diseases: 156; N. variants: 12
Disease: Nicotine withdrawal ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028047
Disease: Nicotine withdrawal
Nicotine withdrawal 		0.010 Biomarker disease BEFREE The aim of the current study was to determine whether treatment with CERC-501, an orally available, potent, and selective kappa opioid receptor antagonist, could alleviate nicotine withdrawal and craving and mitigate mood alterations associated with nicotine withdrawal in humans. 31240842 2019