OPRK1, opioid receptor kappa 1, 4986

N. diseases: 156; N. variants: 12
Disease: positive and negative symptoms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0871099
Disease: positive and negative symptoms
positive and negative symptoms 		0.010 Biomarker phenotype BEFREE Here we present an overview of the kappa system and review various lines of evidence derived from clinical studies for dynorphin and kappa opioid receptor involvement in the pathology of both the positive and negative symptoms of schizophrenia. 31376930 2019