Disease: Alcohol Use Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.030 Biomarker disease BEFREE We characterized the effects of the mu opioid peptide (MOP) receptor agonist buprenorphine and the buprenorphine analog (2S)-2-[(5R,6R,7R,14S)-N-cyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6 methoxymorphinan-7-yl]-3,3-dimethylpentan-2-ol (BU08028), which stimulates MOP and NOP receptors, in a translational nonhuman primate model of AUD. 30970376 2019
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.030 Biomarker disease BEFREE The present results suggest that NOP receptor inhibition rather than activation may represent a valuable approach for treatment of AUD characterized by excessive alcohol consumption such as binge drinking. 31386211 2019
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.030 Biomarker disease BEFREE Thus, it is of high interest to measure the in vivo status of NOP receptors in individuals with alcohol use disorders. 28711193 2018