OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Disease: Opioid abuse ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029095
Disease: Opioid abuse
Opioid abuse 		0.010 Biomarker disease BEFREE Future studies with ICSS could help (a) to clarify mechanisms that increase MOR agonist abuse potential during early opioid exposure or during chronic exposure leading to dependence, (b) to evaluate novel opioids either developed as candidate analgesics with reduced abuse potential or identified as designer opioids being synthesized and distributed for illicit use, and (c) to test candidate pharmacotherapies for treatment of opioid abuse in non-dependent and dependent subjects. 30391425 2019