OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Disease: Alcohol problem ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0549393
Disease: Alcohol problem
Alcohol problem 		0.020 GeneticVariation phenotype BEFREE Polymorphisms in the D4 dopamine receptor (DRD4) gene and the mu-opiate receptor (OPRM1) gene, family history of alcohol problems, age of onset of alcoholism and gender were explored as potential moderators of NTX's effects. 18028530 2008
CUI: C0549393
Disease: Alcohol problem
Alcohol problem 		0.020 GeneticVariation phenotype BEFREE Recent evidence from a number of different studies has suggested that genetic variation in the mu-opioid receptor has a significant influence on clinical presentation of alcohol problems and response to treatment with an opioid antagonist. 16961767 2006