P4HB, prolyl 4-hydroxylase subunit beta, 5034

N. diseases: 222; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 Biomarker phenotype BEFREE Aberrant overexpression of endoplasmic reticulum (ER)-resident oxidoreductase protein disulfide isomerase (PDI) plays an important role in cancer progression. 31149044 2019
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 Biomarker phenotype BEFREE PDIA1 may be a crucial regulator of redox-dependent adaptive processes related to cancer progression. 30760703 2019
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 AlteredExpression phenotype BEFREE Anterior gradient 2 (AGR2), a protein belonging to the protein disulfide isomerase (PDI) family, is overexpressed in multiple cancers and promotes angiogenesis to drive cancer progression. 30647455 2019
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 Biomarker phenotype BEFREE P4HB and PDIA3 are associated with tumor progression and therapeutic outcome of diffuse gliomas. 29207176 2018
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 Biomarker phenotype BEFREE The results suggest that proHB-EGF may play an important role in tumor progression. 23349913 2013