NOX4, NADPH oxidase 4, 50507

N. diseases: 260; N. variants: 17
Disease: Diabetic Angiopathies ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011875
Disease: Diabetic Angiopathies
Diabetic Angiopathies 		0.010 Biomarker disease BEFREE Our results indicate that an MKP-3 pathway might regulate ERK dephosphorylation through Nox4 during CML-triggered endothelial cell dysfunction/injury, suggesting that therapeutic strategies targeting the Nox4/MKP-3 interaction or MKP-3 activation may have clinical implications for diabetic vascular complications. 25014566 2014