NOX4, NADPH oxidase 4, 50507

N. diseases: 260; N. variants: 17
Disease: Hepatitis C ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019196
Disease: Hepatitis C
Hepatitis C 		0.030 AlteredExpression disease BEFREE This pure compound could effectively inhibit viral replication in the infectious cell culture system, displayed strong antioxidant activity by blocking HCV induced generation of reactive oxygen species and suppressed up-regulation of NOX4 and TGF-β mRNA levels. 29224736 2018
CUI: C0019196
Disease: Hepatitis C
Hepatitis C 		0.030 GeneticVariation disease BEFREE One hundred seventy eight naïve HCV patients (49.3% male; 65% HCV genotype 1) with positive HCV RNA were genotyped using specific primers and fluorescent-labeled probes for SNPs rs3017887 in NOX4 and -675 T → A in CYBA. 25888935 2015
CUI: C0019196
Disease: Hepatitis C
Hepatitis C 		0.030 AlteredExpression disease BEFREE Finally, NOX4 expression was elevated in patients with hepatitis C virus (HCV)-derived fibrosis, increasing along the fibrosis degree. 23049784 2012