NOX4, NADPH oxidase 4, 50507

N. diseases: 260; N. variants: 17
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032269
Disease: Pneumococcal Infections
Pneumococcal Infections
0.010 Biomarker group BEFREE Furthermore, Nox4-deficient mice showed substantial reduction in caspase-1 activation and in interleukin (IL)-1β and IL-18 production, and there was improved survival in a mouse model of NLRP3-mediated Streptococcus pneumoniae infection. 27455510 2016