NOX4, NADPH oxidase 4, 50507

N. diseases: 260; N. variants: 17
Disease: Cerebrovascular accident ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.030 AlteredExpression group BEFREE NOX2 and NOX4 overexpression is associated with aggravated ischemic injury, while NOX2/4-deficient mice had reduced stroke size. 29849881 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.030 Biomarker group BEFREE NOX2 and NOX4 may mediate HT in rats with large vessel stroke after mechanical reperfusion. 27075483 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.030 Biomarker group BEFREE While NOX2 appears to be a major source of pathological oxidative stress in the CNS, other NOX isoforms might also be of importance, for example, NOX4 in stroke. 24206089 2014