|
PAI-1 polymorphism
|
0.100 |
Biomarker
|
disease |
BEFREE |
The 4G/4G Genotype of PAI-1 Polymorphism Is Associated with Higher Plasma PAI-1 Concentrations and Mortality in Patients with Severe Sepsis.
|
26066833 |
2015 |
|
PAI-1 polymorphism
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to investigate the relationship between 4G/5G PAI-1 polymorphism with mRNA expression and PAI-1 plasma protein levels in RA patients.
|
22200807 |
2012 |
|
PAI-1 polymorphism
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Plasminogen activator inhibitor-1 (PAI-1) 4 G/5 G polymorphism and endometrial cancer. Influence of PAI-1 polymorphism on tissue PAI-1 antigen and mRNA expression and tumor severity.
|
22055623 |
2012 |
|
PAI-1 polymorphism
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Although increased PAI-1 plasma levels are associated with development of IS in Brazilian young patients, they are not influenced by the 4G/5G PAI-1 polymorphism.
|
21373825 |
2011 |
|
PAI-1 polymorphism
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We may conclude that plasma PAI-1 levels in BC patients could represent a useful prognostic variable for relapse, although PAI-1 polymorphism might not represent a genetic susceptibility factor.
|
19351570 |
2009 |
|
PAI-1 polymorphism
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Plasminogen activator inhibitor-1 (PAI-1) 4G/5G polymorphism and endometriosis. Influence of PAI-1 polymorphism on PAI-1 antigen and mRNA expression.
|
18423526 |
2008 |
|
PAI-1 polymorphism
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We assessed PAI-1 activity and PAI-1 4G/5G polymorphism in hemodialysis (HD) subjects and any association between thrombotic vascular access (VA) events and PAI-1 polymorphism.
|
18609532 |
2008 |
|
PAI-1 polymorphism
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
This study was designed to determine the relative effect of the 4G/5G PAI-1 polymorphism on high plasma PAI-1 levels after adjustment for metabolic syndrome - related variables, and to test if this effect is modified by the smoking status.
|
17199731 |
2007 |
|
PAI-1 polymorphism
|
0.100 |
Biomarker
|
disease |
BEFREE |
The 4G/5G PAI-1 polymorphism determines the endothelial PAI-1 upregulation by Ang II and the inhibitory response to losartan.
|
15194475 |
2004 |
|
PAI-1 polymorphism
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Association of beta-fibrinogen and factor VII polymorphism with plasma fibrinogen and factor VII levels, and no association of PAI-1 polymorphism with plasma PAI-1 levels in hemodialysis patients.
|
12141403 |
2002 |
|
PAI-1 polymorphism
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The observed allele frequencies of the polymorphisms of t-PA, fibrinogen, FVII, ACE, angiotensinogen and the plasma levels of PAI-1 and D-Dimer were in accordance with the low CVD risk in the Inuit, considering the observed associations between these measures and CVD risk in Caucasian populations, but for other measures this was not the case (allele frequencies of the PAI-1 polymorphism, and plasma levels of fibrinogen, FVII and t-PA).
|
10235437 |
1999 |
|
PAI-1 polymorphism
|
0.100 |
Biomarker
|
disease |
BEFREE |
Moreover, the prevalence of PAI-1 induced hypofibrinolysis was strongly related to PAI-1 polymorphism, since it was significantly lower in 5G homozygous patients (28.6%) than in both 4G/5G carriers (55.3%, p <0.001) and 4G homozygous patients (57.9%, p <0.001).
|
9869167 |
1998 |