SERPINE1, serpin family E member 1, 5054

N. diseases: 770; N. variants: 23
Disease: Radiation Nephropathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4054127
Disease: Radiation Nephropathy
Radiation Nephropathy 		0.210 AlteredExpression disease BEFREE Although sulodexide may affect TGF-beta activation in radiation nephropathy, this effect appeared insufficient in this model to inhibit the expressions of PAI-1 and collagen and reduce accumulation of extracellular matrix. 20061322 2010
CUI: C4054127
Disease: Radiation Nephropathy
Radiation Nephropathy 		0.210 Therapeutic disease RGD Modulation of plasminogen activator inhibitor-1 in vivo: a new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition. 8995730 1997