PAPPA, pappalysin 1, 5069

N. diseases: 125; N. variants: 12
Disease: Gestational Diabetes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		0.070 Biomarker phenotype BEFREE Gestational diabetes mellitus and first trimester pregnancy-associated plasma protein A: A case-control study in a Chinese population. 28387061 2018
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		0.070 Biomarker phenotype BEFREE Studies were considered eligible if they were cohorts, case-control studies, reported GDM result, not other types, conducted on singleton pregnancy, measured Serum pregnancy associated plasma protein A in the first trimester and evaluated the relation of first trimester pregnancy associated plasma protein-A and GDM. 29673658 2018
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		0.070 AlteredExpression phenotype BEFREE PROK1 levels and the PROK1/PAPP-A ratios in the SPB and GDM groups were lower than in the uncomplicated group (p < .01). 28675948 2018
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		0.070 AlteredExpression phenotype BEFREE We included original, published, observational studies examining the association of first trimester pregnancy associated plasma protein-A (PAPP-A) and/or free β-human chorionic gonadotropin (free β-hCG) levels with GDM diagnosis. 30048548 2018
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		0.070 GeneticVariation phenotype BEFREE HLA-G del/del and PAPP-A C/C genotypes were more frequent among GDM mothers than controls. 28655969 2017
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		0.070 Biomarker phenotype BEFREE We therefore sought to investigate why circulating PAPP-A concentrations are related to the subsequent risk of GDM and gestational hypertension. 28323969 2017
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		0.070 Biomarker phenotype BEFREE PAPP-A and sHLA-G are independent markers of GDM. 24863523 2014