PAPPA, pappalysin 1, 5069

N. diseases: 125; N. variants: 12
Disease: Ewings sarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0553580
Disease: Ewings sarcoma
Ewings sarcoma 		0.020 Biomarker disease BEFREE Unexpectedly, PAPPA knockout in EWS cell lines induced interferon (IFN)-response genes, including proteins associated with antigen processing/presentation. 30698726 2019
CUI: C0553580
Disease: Ewings sarcoma
Ewings sarcoma 		0.020 Biomarker disease BEFREE In summary, we demonstrate that PAPPA is a first-rate target for TCR-based immunotherapy of ES. 28344885 2017